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Updated: Jun 8, 2026

How to Build a Laser Speckle Contrast Imaging (LSCI) System to Monitor Blood Flow
Published on: November 11, 2010
Relation between the contrast in time integrated dynamic speckle patterns an the power spectral density of their
Matthijs J Draijer1, Erwin Hondebrink, Marcus Larsson
1Biomedical Photonic Imaging, MIRA Institute, University of Twente, the Netherlands. m.j.draijer@alumnus.utwente.nl
Abstract:
Scattering fluid flux can be quantified with coherent light, either from the contrast of speckle patterns, or from the moments of the power spectrum of intensity fluctuations. We present a theory connecting these approaches for the general case of mixed static-dynamic patterns of boiling speckles without prior assumptions regarding the particle dynamics. An expression is derived and tested relating the speckle contrast to the intensity power spectrum. Our theory demonstrates that in speckle contrast the concentration of moving particles dominates over the contribution of speed to the particle flux. Our theory provides a basis for comparison of both approaches when used for studying tissue perfusion.
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