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Related Concept Videos

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Pharmacogenomics: Identification of New Drug Targets01:29

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Related Experiment Video

Updated: Jun 8, 2026

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
07:15

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on: January 16, 2019

Specifying WHO recommendation: moving toward disease-specific guidelines.

Jan Gaertner1, Juergen Wolf, Christoph Ostgathe

  • 1Department of Palliative Medicine, University Hospital of Cologne, Cologne, Germany. jan.gaertner@uk-koeln.de

Journal of Palliative Medicine
|October 15, 2010
PubMed
Summary

This study introduces a new standard operating procedure (SOP) for early palliative care (PC) integration in lung cancer patients. The SOP recommends PC alongside cancer therapy to improve care coordination and outcomes.

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Last Updated: Jun 8, 2026

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
07:15

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on: January 16, 2019

Area of Science:

  • Oncology
  • Palliative Care
  • Healthcare Management

Background:

  • The World Health Organization (WHO) advocates for early palliative care (PC) integration.
  • Despite administrative directives and a PC hospital support team, lung cancer patients received PC late.
  • This necessitated the development of disease-specific standard operating procedures (SOPs).

Purpose of the Study:

  • To develop and implement disease-specific SOPs for early palliative care integration in lung cancer patients.
  • To address deficiencies in the late delivery of PC to lung cancer patients.
  • To provide clear guidelines for timely and effective PC integration.

Main Methods:

  • Developed a consensus SOP for palliative care in lung cancer.
  • Defined specific criteria ('green flags') for early PC integration.
  • Recommended simultaneous integration of PC with tumor-specific therapy.

Main Results:

  • The SOP recommends regular specialized PC for all lung cancer patients without curative options.
  • Integration of PC is advised concurrently with the initiation of tumor-specific therapy.
  • Initial PC delivery is recommended at the same location as specific cancer treatment.

Conclusions:

  • This SOP provides the first disease-specific guidelines for integrating PC into comprehensive lung cancer care.
  • It defines 'green flags' for early PC integration and recommends parallel delivery with anticancer therapy.
  • These disease-specific algorithms aim to reduce uncertainty regarding early PC integration.