Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cryptococcal Meningitis

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...

Pulmonary Tuberculosis I

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...

Skin Diseases and Disorders

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

Immunodeficiency Diseases

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency disorders...

Staphylococcal Skin Infections

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Shallow and ensemble deep randomized neural network for anomaly detection.

Neural networks : the official journal of the International Neural Network Society·2025

Same author

Graph Embedded Intuitionistic Fuzzy Random Vector Functional Link Neural Network for Class Imbalance Learning.

IEEE transactions on neural networks and learning systems·2024

Same author

Incidental lymphadenopathy in renal transplantation.

Annals of the Royal College of Surgeons of England·2023

Same author

Reply to: Considerations on "impact of centralization of services on outcomes in a rare tumour: Retroperitoneal sarcomas".

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2019

Same author

Impact of centralization of services on outcomes in a rare tumour: Retroperitoneal sarcomas.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2018

Same author

A case report of an angiomyxoma in the liver.

Annals of the Royal College of Surgeons of England·2018

Search research articles

Related Experiment Videos

Pyoderma gangrenosum in HIV patient.

S K Sayal¹, A K Malik, S Banerjee

¹Department of Dermatology and Venereology, AFMC, Pune - 411040, India.

Indian Journal of Dermatology, Venereology and Leprology

|October 15, 2010

Summary

Pyoderma gangrenosum (PG) is rare in HIV patients. This case study details a 30-year-old woman with HIV presenting with multiple lower limb ulcerations indicative of PG.

Area of Science:

Dermatology
Infectious Diseases
Immunology

Background:

Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis.
Previous reports of PG in HIV-infected individuals are very limited.
HIV infection can alter immune responses, potentially influencing dermatological conditions.

Purpose of the Study:

To report a case of pyoderma gangrenosum in a patient with HIV infection.
To highlight the infrequent association between PG and HIV.
To contribute to the limited literature on this comorbidity.

Main Methods:

Case report presentation.
Clinical description of a 30-year-old female patient.
Documentation of presenting symptoms and medical history, including HIV status.

Related Experiment Videos

Main Results:

The patient presented with multiple ulcerations on her lower limbs.
The ulcerations were clinically characteristic of pyoderma gangrenosum.
The patient had a confirmed diagnosis of HIV infection.

Conclusions:

Pyoderma gangrenosum can occur in patients with HIV infection, although it is uncommon.
This case underscores the importance of considering PG in the differential diagnosis of ulcerative skin lesions in HIV-positive individuals.
Further research may be needed to understand the specific mechanisms linking HIV and PG.