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Determination of imipenem in human plasma, urine and tissue by high-performance liquid chromatography
G Carlucci1, L Biordi, C Vicentini
1Dipartimento di Chimica, Università degli Studi dell'Aquila, Italy.
Journal of Pharmaceutical and Biomedical Analysis
|January 1, 1990
Abstract:
A simple and reliable HPLC method is described for the new beta-lactam antibiotic imipenem; suitable extraction procedures for the drug in human plasma, urine and prostatic tissue are described. The figures of merit for the assays are reported and examples given of their application.