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Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Updated: Jun 8, 2026

A 3D Organotypic Melanoma Spheroid Skin Model

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

Pagetoid melanoma.

G Ravichandran¹, S Premalatha

¹From the Department of Dermatology, Stanley Medical College and Hospital Chennai-600 001, India, .

Indian Journal of Dermatology, Venereology and Leprology

|October 15, 2010

Summary

This summary is machine-generated.

This case report details a pagetoid melanoma, highlighting its rare location, significant size, and unique histopathological features like suprabasal lacunae.

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Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Spatial and Temporal Control of Murine Melanoma Initiation from Mutant Melanocyte Stem Cells

Published on: June 7, 2019

Area of Science:

Dermatopathology
Oncology

Background:

Pagetoid melanoma is a rare variant of melanoma.
Melanoma can present with diverse histopathological features.

Purpose of the Study:

To report a unique case of pagetoid melanoma.
To describe unusual characteristics of this melanoma variant.

Main Methods:

Histopathological examination of a skin lesion.
Clinical correlation of findings.

Main Results:

The pagetoid melanoma was located at an unusual site.
The lesion was notably large.
Histopathology revealed the presence of suprabasal lacunae.

Conclusions:

This case expands the understanding of pagetoid melanoma presentation.
Suprabasal lacunae may be a feature in some pagetoid melanomas.
Unusual sites and sizes of melanoma should be considered in diagnosis.