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Related Concept Videos

Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Chronic Inflammation: Introduction01:12

Chronic Inflammation: Introduction

Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Microbiome of the Eye01:22

Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
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Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...

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Related Experiment Video

Updated: Jun 8, 2026

A Rat Model of Compound Acne
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A Rat Model of Compound Acne

Published on: November 1, 2024

Chronic folliculitis - A clinico-epidemiological study.

P Prasad1, V Anandhi, M Jaya

  • 1Department of Dermatology and Microbiology, Rajah Muthiah Medical College and Hospital, Annamalai University, Annamalainagar - 608 002, India, .

Indian Journal of Dermatology, Venereology and Leprology
|October 15, 2010
PubMed
Summary

Chronic folliculitis of legs (CFL) primarily affects young adults, often presenting with severe itching before lesion onset. Staphylococcus aureus is frequently isolated, with lesions typically localized to the legs.

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Last Updated: Jun 8, 2026

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03:10

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Published on: November 1, 2024

Area of Science:

  • Dermatology
  • Epidemiology
  • Microbiology

Background:

  • Chronic folliculitis of the legs (CFL) is a skin condition requiring further epidemiological understanding.
  • Limited data exists on the clinical presentation and causative agents of CFL in affected populations.

Purpose of the Study:

  • To conduct a clinico-epidemiological study of chronic folliculitis of the legs.
  • To identify the predominant age group, clinical features, and microbiological profile of CFL patients.

Main Methods:

  • A study including 50 male patients diagnosed with chronic folliculitis of the legs.
  • Clinical data collection on patient demographics, symptoms (pruritus), lesion morphology (papules vs. pustules), and lesion distribution.
  • Microbiological analysis to isolate causative organisms, specifically Staphylococcus aureus.

Main Results:

  • CFL predominantly affected young adults aged 16-25 years.
  • Severe pruritus was reported in 86% of patients, often preceding new lesion development.
  • Follicular papules were more common (58%) than pustules, and Staphylococcus aureus was isolated in 72.5% of cases.
  • Lesions were most commonly confined to the legs (50%), extending to the thighs in 28%.

Conclusions:

  • Chronic folliculitis of the legs is a condition primarily seen in young adult males.
  • Pruritus and Staphylococcus aureus infection are significant clinical features of CFL.
  • Understanding these epidemiological and clinical aspects can aid in diagnosis and management strategies.