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Updated: Jun 8, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Relapse in psoriasis after methotrexate
1Department of Skin, STD and Leprology, J JM on Medical College, Davengere - 577 004, India, .
Abstract:
20 patients, 12 males and 8 females with chronic palque psoriasis, not responding to conventional therapy were treated with methotrexate (MTX) in the dose of 15 mg/week, 3 doses, 12th hourly apart, for 4 - 12 weeks. All the cases in which MTX was stopped after attaining remission and giving maintenance therapy of 5 mg/week for 8 weeks had relapsed within 6 weeks to 12 weeks. Premethotrexate or postmethotrexate laboratory investigations were within normal limits. No significant side effects were noted.
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