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Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
12:59

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes

Published on: September 26, 2013

IL-17: important for host defense, autoimmunity, and allergy?

F Eun-Hyung Lee1, Steve N Georas, Lisa A Beck

  • 1Division of Pulmonary and Critical Care Medicine, University of Rochester Medical Center, Rochester, New York, USA.

The Journal of Investigative Dermatology
|October 15, 2010
PubMed
Summary

Interleukin-17a (IL-17a) may boost immunoglobulin E (IgE) production, potentially linking T-cell responses to allergic diseases like asthma. Further research is needed to clarify the exact mechanism and its implications for distinct immune phenotypes.

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