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Stem Cell Therapy for Tissue Regeneration

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Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
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Related Experiment Video

Updated: Jun 8, 2026

Intracerebral Transplantation and In Vivo Bioluminescence Tracking of Human Neural Progenitor Cells in the Mouse Brain

Intracerebral Transplantation and In Vivo Bioluminescence Tracking of Human Neural Progenitor Cells in the Mouse Brain

Published on: January 27, 2022

Cell-based therapy for stroke.

¹National Institute on Drug Abuse, I.R.P., 251 Bayview BLVD, Baltimore, MD 21224, USA. luoy@mail.nih.gov

Journal of Neural Transmission (Vienna, Austria : 1996)

|October 15, 2010

Summary

This summary is machine-generated.

Cell-based therapies offer new hope for stroke recovery by leveraging the brain's natural healing processes. These strategies aim to repair brain damage or stimulate the brain's own stem cells, potentially opening a new treatment window.

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Intra-Arterial Delivery of Neural Stem Cells to the Rat and Mouse Brain: Application to Cerebral Ischemia

Intra-Arterial Delivery of Neural Stem Cells to the Rat and Mouse Brain: Application to Cerebral Ischemia

Published on: June 26, 2020

Area of Science:

Neuroscience
Regenerative Medicine
Stem Cell Biology

Background:

Current stroke treatments, like thrombolytic agents, have limited effectiveness due to narrow therapeutic time windows.
The brain exhibits regenerative potential for weeks post-stroke, suggesting a secondary therapeutic window.
Cell-based therapies present a promising avenue for stroke treatment by addressing these limitations.

Purpose of the Study:

To review recent advancements in cell-based therapies for stroke treatment.
To explore strategies involving exogenous cell transplantation and endogenous stem cell activation.
To highlight the potential of cell therapies in promoting neurogenesis and functional recovery after stroke.

Main Methods:

Review of current literature on cell-based therapies for stroke.
Analysis of two primary cell therapy strategies: exogenous cell transplantation and endogenous stem/progenitor cell enhancement.
Discussion of stem cell research, including adult stem cells and induced pluripotent stem cells.

Main Results:

Cell-based therapies include transplanting external cells or stimulating the brain's own stem cells.
Advances in stem cell technology offer significant opportunities for transplantation therapies.
Understanding endogenous neurogenesis mechanisms is key to developing new stroke treatments.

Conclusions:

Cell-based therapies hold significant promise for stroke treatment, potentially overcoming the limitations of current approaches.
Both transplantation of exogenous cells and enhancement of endogenous stem cells are viable strategies.
Further research into neurogenesis and stem cell biology can lead to improved functional recovery after stroke.