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Updated: Jun 8, 2026

Cryo-Electron Tomography Remote Data Collection and Subtomogram Averaging
Published on: July 12, 2022
[Physical aspects of different tomosynthesis systems]
1Zentrum für Medizinische Physik und Biomedizinische Technik, Medizinische Universität Wien, Währinger Gürtel 18-20, A-1090 Wien, Österreich. friedrich.semturs@meduniwien.ac.at
Abstract:
Digital breast tomosynthesis (DBT) is a new image processing technique based on digital mammography technology. Image slices of the stationary compressed breast are reconstructed from multiple images taken at different angles of the X-ray tube at the same time. The main goal is to achieve a similar radiation dose exposure as common encountered in traditional digital mammography. One of the key advantages of DBT is that lesions are less likely to be hidden amongst normal tissues as they are in traditional digital mammography. This way the quality of diagnosis can be improved, especially for dense breasts. Current DBT implementations from several manufacturers differ in certain features such as scanning angle, number of projections, scanning time, pixel size, reconstruction methods and type of tube movement. A comparison and description of these different characteristics as well as a discussion on the proposed number of imaging planes and related radiation dose requirements are given.
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