Related Experiment Video
Updated: Jun 8, 2026

Computational Analysis of the Caenorhabditis elegans Germline to Study the Distribution of Nuclei, Proteins, and the Cytoskeleton
Published on: April 19, 2018
The nuts and bolts of germ-cell migration
Katsiaryna Tarbashevich1, Erez Raz
1Institute of Cell Biology, Center for Molecular Biology of Inflammation, Von-Esmarch-Str. 56, 48149, Münster University, 48147 Münster, Germany.
Abstract:
In many species, primordial germ cells (PGCs) migrate from the position where they are specified to the site where the gonad develops, where they differentiate into sperm and egg. Germ cells thus serve as an excellent model for studying cell migration in the context of the live organism. In recent years, a number of cues directing the migration of the cells towards their target were identified and some of the relevant molecules and biochemical pathways were revealed. In this review we present those results, focusing on 'cell mechanics' of the process including cell adhesion, traction generation and cell polarization.
More Related Videos
Related Concept Videos
Cytoskeletal Coordination in Cell Migration
Cell Migration
Cell Migration
Gastrulation
Spermatogenesis
Spermatogenesis
The process of spermatogenesis can be divided into mitosis, meiosis, and spermiogenesis. During mitosis, the spermatogonia or stem cells divide to produce two identical daughter cells, type A and B spermatogonia. Type-A...
