Oral psoralens vs injection placental extract plus oral psoralens in vitiligo

One hundred patients with vitiligo were enrolled from out patient department from the year 1990-91 for screening the therapeutic effect of injection placental extract (Placentrex). Patients were divided into two groups of 50 each, age and sex matched and were given two different regimens of treatment. In Regimen- I, patients were given oral psoralens followed by sun exposure after 2 hours and then application of topical betamethasone-17 valerate. In Regimen-ll patients were given treatment as in regimen-l along with injection of placental extract. It was found that initial response rate of Regimen-ll therapy was 36% higher than Regimen-l whereas total efficacy of R-ll was 20% higher than R-l.