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Development and Functional Characterization of Murine Tolerogenic Dendritic Cells

Development and Functional Characterization of Murine Tolerogenic Dendritic Cells

Published on: May 18, 2018

Dowling-degos disease.

R Sharma¹, V K Sharma

¹Bishen Skin Centre,M-69, Marris Road,Aligargh-202001, India.

Indian Journal of Dermatology, Venereology and Leprology

|October 16, 2010

Summary

This summary is machine-generated.

This study describes four cases of Dowling-Degos disease, a rare skin condition. All patients exhibited characteristic reticulate, flexural pigmentation and perioral pitted scars.

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Area of Science:

Dermatology
Genetics

Background:

Dowling-Degos disease is a rare genodermatosis.
It is characterized by progressive reticulate, reticular, and flexural hyperpigmentation.

Purpose of the Study:

To describe clinical features of Dowling-Degos disease.
To highlight common diagnostic indicators.

Main Methods:

Case series review.
Clinical observation and documentation.

Main Results:

Four cases of Dowling-Degos disease were identified.
All patients presented with reticulate, flexural pigmentation.
Perioral pitted scars were observed in all four patients.
One patient also exhibited milia.

Conclusions:

Reticulate, flexural pigmentation and perioral pitted scars are key indicators of Dowling-Degos disease.
Early recognition aids in timely diagnosis and management.