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Updated: Jun 8, 2026

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
Relapse, reinfection or inadequate MDT ?
1, R Bharti
1From Upgraded Urban Leprosy Centre, Civil Hospital, Amritsar-143001, India.
Abstract:
Relapse by all standard definitions is reported in a middle aged woman after PB MDT. Since she belonged to a family of treated leprosy sufferers (husband and his elder brother) and her daughter has now developed infectious type of leprosy, the possibility of reinfection can also not be ruled out.
Insights
A middle-aged woman experienced leprosy relapse after treatment. Given her family history and her daughter
Area of Science:
- Medical Science
- Infectious Diseases
- Dermatology
Background:
- Leprosy, a chronic infectious disease, requires ongoing monitoring post-treatment.
- Relapse and reinfection are significant concerns in leprosy management.
Purpose of the Study:
- To analyze a case of leprosy relapse in a middle-aged woman.
- To investigate potential causes of relapse, including reinfection, in the context of a leprosy-affected family.
Main Methods:
- Clinical case review.
- Epidemiological investigation of family contacts.
Main Results:
- A middle-aged woman presented with leprosy relapse following paucibacillary multidrug therapy (PB MDT).
- The patient's family includes individuals with a history of treated leprosy and a daughter with infectious leprosy.
Conclusions:
- The patient's relapse highlights the importance of long-term surveillance in leprosy.
- The familial clustering of leprosy cases suggests a potential for reinfection or shared environmental exposure, warranting further investigation.
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