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Quantifying the Modulation of Elastase Enzyme Activity Through Colorimetric Analysis
Published on: January 17, 2025
Wrinkles due to idiopathic dermal elastolysis.
1Department of Skin and STD, IG Medical College, Shimla - 171001, India.
Indian Journal of Dermatology, Venereology and Leprology
|October 16, 2010
Summary
A 9-year-old boy experienced localized skin wrinkling and follicular prominence. Histopathology revealed a significant loss of dermal elastic tissue in the affected area.
Area of Science:
- Dermatology
- Histopathology
- Pediatric Dermatology
Background:
- Skin aging and elasticity are crucial for skin health.
- Loss of elastic tissue can lead to visible skin changes.
Purpose of the Study:
- To report a case of localized skin wrinkling with follicular prominence in a pediatric patient.
- To investigate the histopathological basis of these skin changes.
Main Methods:
- Clinical examination of skin lesions.
- Histopathological analysis of skin biopsy specimens.
- Microscopic evaluation for dermal elastic tissue.
Main Results:
- Clinical presentation included localized skin wrinkling and follicular prominences.
- Histopathological findings demonstrated a marked loss of dermal elastic tissue in the affected skin.
- The changes were observed in a 9-year-old male patient.
Conclusions:
- Localized dermal elastic tissue loss can manifest as premature skin aging signs in children.
- This case highlights the importance of histopathological examination for diagnosing rare skin conditions.
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