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Related Concept Videos

Trihybrid Crosses02:27

Trihybrid Crosses

Trihybrid Crosses
Some of Mendel’s crosses examined three pairs of contrasting characteristics. Such a cross is called a trihybrid cross. A trihybrid cross is a combination of three individual monohybrid crosses. For example, plant height (tall vs. short), seed shape (round vs. wrinkled), and seed color (yellow vs. green).
The F1 generation plants of a trihybrid cross are heterozygous for all three traits and produce eight gametes. Upon self-fertilization, these gametes have an equal chance to...
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Pedigree Analysis

Overview
Pedigree Analysis01:35

Pedigree Analysis

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Non-nuclear Inheritance01:29

Non-nuclear Inheritance

Most DNA resides in the nucleus of a cell. However, some organelles in the cell cytoplasm⁠—such as chloroplasts and mitochondria⁠—also have their own DNA. These organelles replicate their DNA independently of the nuclear DNA of the cell in which they reside. Non-nuclear inheritance describes the inheritance of genes from structures other than the nucleus.
Non-nuclear Inheritance01:29

Non-nuclear Inheritance

Most DNA resides in the nucleus of a cell. However, some organelles in the cell cytoplasm⁠—such as chloroplasts and mitochondria⁠—also have their own DNA. These organelles replicate their DNA independently of the nuclear DNA of the cell in which they reside. Non-nuclear inheritance describes the inheritance of genes from structures other than the nucleus.
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Multiple Allele Traits

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Related Experiment Video

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In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
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Accessory tragi in three successive generations.

N S Vora1, J N Dave, S V Shah

  • 1Department of Skin and VD, Bapunagar General Hospital, (ESIS) Ahmedabad-380024, India.

Indian Journal of Dermatology, Venereology and Leprology
|October 16, 2010
PubMed
Summary
This summary is machine-generated.

Accessory tragi, a rare congenital condition, were observed in a 40-year-old man and his family. The study suggests an autosomal dominant inheritance pattern due to its presence across three generations.

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Area of Science:

  • Dermatology
  • Clinical Genetics
  • Medical Genetics

Background:

  • Accessory tragi are rare congenital malformations.
  • Familial occurrence of accessory tragi suggests a genetic basis.

Purpose of the Study:

  • To investigate the clinical and histopathological features of accessory tragi.
  • To determine the mode of inheritance of accessory tragi in a familial case.

Main Methods:

  • Clinical examination of affected individuals.
  • Histopathological analysis of accessory tragi lesions.
  • Pedigree analysis to assess inheritance patterns.

Main Results:

  • A 40-year-old male presented with clinical and histopathological findings consistent with accessory tragi.
  • The condition demonstrated vertical transmission through three successive generations.
  • Both male and female family members were affected, indicating transmission across sexes.

Conclusions:

  • The observed pattern of inheritance, involving both sexes and spanning three generations, strongly suggests an autosomal dominant mode of inheritance for accessory tragi.
  • Accessory tragi may represent a distinct genetic entity with a predictable inheritance pattern.