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Lichen dyschromicum perstans
1Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh-160012, India.
Indian Journal of Dermatology, Venereology and Leprology
|October 16, 2010
Summary
A newly identified hyperpigmentation disorder, lichen dyschromicum perstans, affects middle-aged adults, presenting as persistent, symmetrical skin lesions on the face and trunk. Histopathology shows lichenoid reactions, distinguishing it from lichen planus.
Area of Science:
- Dermatology
- Pathology
Background:
- Hyperpigmentation disorders present a diagnostic challenge.
- A common, persistent skin condition affecting middle-aged individuals was observed.
- Lesions typically appear on the face, neck, and upper trunk.
Purpose of the Study:
- To describe a novel disorder of hyperpigmentation.
- To differentiate this condition from existing dermatoses.
- To establish preliminary diagnostic criteria based on clinical and histopathological findings.
Main Methods:
- Clinical observation of affected individuals.
- Detailed description of lesion distribution, symmetry, and color.
- Histopathological examination of skin biopsies.
- Comparison with clinical features of lichen planus.
Main Results:
- The disorder commonly affects middle-aged individuals.
- Lesions are typically bilaterally symmetrical, affecting the face, neck, and trunk.
- Pigmentation varies (grey to black) and persists long-term; oral mucosa is rarely involved.
- Histopathology revealed lichenoid tissue reactions, distinct from lichen planus.
Conclusions:
- A new disorder, tentatively named lichen dyschromicum perstans, is proposed.
- The condition is characterized by persistent, symmetrical hyperpigmentation with lichenoid tissue reactions.
- Further research is needed to clarify its relationship with other pigmentary disorders.
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