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Mutilating keratoderma with deaf-mutism.

S Rastogi¹, P Kumar, R D Mukhija

¹Department of Dermatology, BRD Medical College, Gorakhpur-273013, India.

Indian Journal of Dermatology, Venereology and Leprology

|October 16, 2010

Summary

This summary is machine-generated.

Mutilating keratoderma, a rare skin condition causing severe palm and sole thickening and digit constriction, was diagnosed in a deaf and dumb patient. Histopathology confirmed the clinical findings, highlighting the importance of this diagnostic approach.

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Area of Science:

Dermatology
Medical Genetics

Background:

Mutilating keratoderma is a rare condition characterized by progressive hyperkeratosis and pseudoainhum.
Early onset and associated congenital anomalies, such as deafness, can occur.

Purpose of the Study:

To present a case of mutilating keratoderma with congenital deafness.
To emphasize the diagnostic role of histopathology in confirming the condition.

Main Methods:

Clinical presentation of a 30-year-old female patient with hyperkeratosis and digit constriction.
Histopathological examination of skin lesions.

Main Results:

The patient exhibited typical lesions of mutilating keratoderma, including hyperkeratosis of palms and soles since infancy.
Digit constriction was noted by age 5.
Histopathological findings supported the clinical diagnosis.

Conclusions:

Mutilating keratoderma can present with associated congenital conditions like deafness.
Histopathological examination is crucial for accurate diagnosis of this rare disorder.