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Related Concept Videos

Centrifugation01:05

Centrifugation

Centrifugation is a separation technique based on differences in density or size. It is commonly used to separate solids from aqueous interferents. During centrifugation, the sample is placed in centrifugation tubes and spun at high angular velocity, which allows centrifugal force to act differentially on the different densities or masses of the components. After spinning, the supernatant liquid is decanted. Depending on the specific application, either the pellet or the supernatant is retained...
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Assessment of the Cardiovascular System III: Palpation01:27

Assessment of the Cardiovascular System III: Palpation

Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above the...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
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Disorders of Erythrocytes01:27

Disorders of Erythrocytes

Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
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On the other...
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Rheumatic Heart Disease I: Introduction

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Related Experiment Video

Updated: Jun 8, 2026

Precision Implementation of Minimal Erythema Dose (MED) Testing to Assess Individual Variation in Human Inflammatory Response
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Published on: October 3, 2019

Erythema annulare centrifugum.

A K Roy1, S K Ghosh

  • 1Department of Dermatology, RG Kar Medical College, Calcutta-700004, India.

Indian Journal of Dermatology, Venereology and Leprology
|October 16, 2010
PubMed
Summary

A 45-year-old woman experienced recurring polycyclic red skin lesions for two years. Diagnosis confirmed erythema annulare centrifugum after a biopsy, with no identifiable cause.

Area of Science:

  • Dermatology
  • Pathology

Background:

  • Erythema annulare centrifugum (EAC) is a rare, reactive erythema characterized by annular or polycyclic lesions.
  • The etiology of EAC is often idiopathic, but it can be associated with infections, medications, and malignancies.

Purpose of the Study:

  • To present a case of a 45-year-old female with a prolonged history of recurrent polycyclic erythematous lesions.
  • To highlight the diagnostic process and histopathological findings consistent with erythema annulare centrifugum.

Main Methods:

  • Clinical observation over a two-year period.
  • Dermatopathological examination of lesional biopsy.

Main Results:

  • Recurrent eruption of polycyclic erythematous lesions was observed.

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  • Biopsy findings were characteristic of erythema annulare centrifugum.

    • Conclusions:

    • The case illustrates a diagnostic challenge in identifying the cause of chronic, recurrent EAC.
    • Histopathological confirmation remains crucial for diagnosing erythema annulare centrifugum in the absence of a clear etiology.