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Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
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Unilateral darier's disease.

R V Singh1, S Singh, S S Pandey

  • 1Department of Dermatology, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, India.

Indian Journal of Dermatology, Venereology and Leprology
|October 16, 2010
PubMed
Summary
This summary is machine-generated.

This report details a rare case of Darier's disease presenting unilaterally in a young male. The patient exhibited typical clinical and histopathological signs, highlighting disease variations.

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Area of Science:

  • Dermatology
  • Genetics
  • Histopathology

Background:

  • Darier's disease, also known as Darier-White disease, is a rare autosomal dominant genodermatosis.
  • It is characterized by the development of crusty, itchy patches and bumps on the skin.
  • Variations in clinical presentation have been documented, but unilateral involvement is uncommon.

Purpose of the Study:

  • To report a unique case of Darier's disease with unilateral manifestation.
  • To correlate clinical findings with histopathological features in this specific presentation.
  • To contribute to the understanding of Darier's disease heterogeneity.

Main Methods:

  • Clinical examination of a young male patient.
  • Dermatopathological analysis of skin biopsies.
  • Review of relevant literature on Darier's disease variations.

Main Results:

  • The patient presented with unilateral skin lesions consistent with Darier's disease.
  • Histopathological examination confirmed the diagnosis, showing characteristic features of Darier's disease.
  • The findings support the existence of asymmetric presentations of the condition.

Conclusions:

  • Unilateral involvement can occur in Darier's disease.
  • Clinical and histopathological features remain typical despite asymmetric presentation.
  • This case expands the spectrum of Darier's disease manifestations.