Long-distance transport of macromolecules through the phloem

Long-distance phloem transport of small metabolites has long been the subject of many different studies concentrating on resource allocation and signalling between plant organs. Also, phloem movement of viruses has long been examined as the route for systemic infection of the plant. Only recently, the transport of macromolecules, such as proteins and nucleic acids, has received increasing attention because they are regarded as being a new class of potential information-transmitter. A set of recent publications allows the first insights into the important roles that phloem-mobile macromolecules might play in the regulation of development and the responses to stress. Furthermore, they start to shed light on the mechanisms involved in systemic macromolecule transport.