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Related Experiment Video

Updated: Jun 8, 2026

A Video Demonstration of Preserved Piloting by Scent Tracking but Impaired Dead Reckoning After Fimbria-Fornix Lesions in the Rat

A Video Demonstration of Preserved Piloting by Scent Tracking but Impaired Dead Reckoning After Fimbria-Fornix Lesions in the Rat

Published on: April 24, 2009

Sources of the spatial code within the hippocampus.

Mark P Brandon¹, Michael E Hasselmo

¹Center for Memory and Brain, Department of Psychology and Program in Neuroscience Boston University, 2 Cummington Street, Boston, MA 02215 USA.

F1000 Biology Reports

|October 16, 2010

Summary

Neurons in the hippocampus are crucial for spatial navigation. Specific pathways from the entorhinal cortex to the hippocampus significantly influence an animal's perception of its location.

More Related Videos

Horizontal Hippocampal Slices of the Mouse Brain

Horizontal Hippocampal Slices of the Mouse Brain

Published on: September 22, 2020

Related Experiment Videos

Last Updated: Jun 8, 2026

A Video Demonstration of Preserved Piloting by Scent Tracking but Impaired Dead Reckoning After Fimbria-Fornix Lesions in the Rat

A Video Demonstration of Preserved Piloting by Scent Tracking but Impaired Dead Reckoning After Fimbria-Fornix Lesions in the Rat

Published on: April 24, 2009

Horizontal Hippocampal Slices of the Mouse Brain

Horizontal Hippocampal Slices of the Mouse Brain

Published on: September 22, 2020

Area of Science:

Neuroscience
Spatial Cognition
Neuroanatomy

Background:

The hippocampus plays a vital role in spatial memory and navigation.
Information about an animal's location is processed within the hippocampus.
Afferent pathways from the entorhinal cortex are the primary source of hippocampal input.

Purpose of the Study:

To investigate the role of distinct entorhinal cortex afferent pathways in hippocampal spatial information processing.
To enhance the understanding of how specific neural inputs contribute to an animal's sense of place.

Main Methods:

Analysis of afferent pathways connecting the entorhinal cortex to the hippocampus.
Examination of neural activity patterns related to spatial perception.
Utilizing recent research findings to correlate pathway function with location information.

Main Results:

Individual afferent pathways from the entorhinal cortex demonstrate specific contributions to hippocampal function.
These pathways are critical for encoding and retrieving information about an animal's position.
The distinct roles of these pathways refine our understanding of hippocampal spatial mapping.

Conclusions:

Specific entorhinal cortex to hippocampus pathways are essential for accurate location perception.
Understanding these pathways deepens our knowledge of hippocampal mechanisms in spatial navigation.
This research highlights the importance of dissecting neural circuits for comprehending cognitive functions.