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Updated: Jun 8, 2026

An Intestinal Gut Organ Culture System for Analyzing Host-Microbiota Interactions
Published on: June 30, 2021
Advances in understanding the interaction between the gut microbiota and adaptive mucosal immune responses
Abstract:
Commensal gut bacteria are necessary for the complete development of mucosal innate and adaptive immunity and thus may influence intestinal and systemic immune disorders. Recent work has advanced our understanding of this association by identification of a single taxon of the murine microbiota which can stimulate T-cell development and differentiation. It is hoped that further characterization of the mechanisms involved will enable targeted manipulation of the microbiota-immune system relationship.
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