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Recent advances in the management of hypertension

José Antonio García-Donaire1, Luis M Ruilope

  • 1Hypertension Unit Hospital 12 de Octubre, 28041, Madrid Spain.

F1000 Medicine Reports
|October 16, 2010
PubMed

Insights

Achieving normal blood pressure (BP) is adequate for early-stage cardiorenal disease. However, very low BP goals may pose risks for patients with advanced cardiorenal conditions.

Area of Science:

  • Cardiology
  • Nephrology
  • Hypertension Management

Background:

  • Recent reports question the adequacy of blood pressure (BP) control in high-risk hypertensive patients.
  • A reappraisal of European Society of Hypertension guidelines addresses these concerns.

Purpose of the Study:

  • To comment on and extend the discussion regarding BP control adequacy in high-risk hypertensive patients.
  • To evaluate the risks and benefits of different BP goals across the cardiorenal continuum.

Main Methods:

  • Review of recent literature and guidelines on hypertension management.
  • Analysis of BP control strategies in the context of cardiorenal disease progression.

Main Results:

  • A low BP goal may be risky in advanced cardiorenal disease.
  • Attaining normal BP levels is likely adequate in earlier stages of cardiorenal disease.

Conclusions:

  • BP targets should be individualized based on the stage of cardiorenal disease.
  • Caution is advised with overly aggressive BP lowering in advanced stages.

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