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Related Experiment Video

Updated: Jun 8, 2026

Real-time Breath Analysis by Using Secondary Nanoelectrospray Ionization Coupled to High Resolution Mass Spectrometry

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Published on: March 9, 2018

Exhaled breath analysis: The new interface between medicine and engineering.

Alquam Mashir¹, Raed A Dweik

¹Department of Pathobiology/Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, United States.

Advanced Powder Technology : the International Journal of the Society of Powder Technology, Japan

|October 16, 2010

Summary

Exhaled breath testing offers a non-invasive, low-cost, and safe diagnostic method. Advancing this field requires collaboration between technical, medical, and industry experts for clinical application and commercialization.

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Area of Science:

Biomedical Engineering
Clinical Diagnostics
Pulmonology

Background:

Exhaled breath testing is an emerging non-invasive diagnostic tool.
It holds potential for evaluating various health and disease states, particularly in the lungs.
Advantages include being non-invasive, cost-effective, and safe compared to traditional methods.

Purpose of the Study:

To highlight the growing importance of exhaled breath testing.
To identify key requirements for advancing the field of breath analysis.
To emphasize the need for interdisciplinary collaboration.

Main Methods:

This study is a review and perspective piece.
It analyzes the current state and future potential of exhaled breath testing.
It identifies the necessary components for successful clinical translation.

Main Results:

Exhaled breath testing is a significant non-invasive diagnostic approach.
Collaboration is crucial for device development and clinical integration.
Bridging the gap between technology, clinical needs, and commercialization is essential.

Conclusions:

Further advancement in exhaled breath testing necessitates strong partnerships.
Integrating technical, medical, and commercial expertise will drive innovation.
Successful commercialization hinges on collaborative efforts to bring devices to market.