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Paramagnetic nanofibrous composite films enhance the osteogenic responses of pre-osteoblast cells
Jie Meng1, Yu Zhang, Xiaojin Qi
1Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Nanoscale
|October 16, 2010
Abstract:
In this work, a paramagnetic nanofibrous composite film was fabricated with poly lactide, hydroxyapatite and γ-Fe(2)0(3) nanoparticles using the electrospinning technique. The composite film significantly enhanced the proliferation, differentiation and ECM secretion of the osteoblast cells under a static magnetic field, which offers promising application potentials in bone tissue engineering and bone regeneration therapy.

