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Related Concept Videos

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Huntington Disease l: Introduction

Huntington disease or HD is a progressive, fatal neurodegenerative disorder inherited in an autosomal dominant pattern.PathophysiologyIt is caused by expansion of the CAG trinucleotide repeat in the HTT gene on chromosome 4 (4p16.3), producing an abnormal huntingtin protein with an expanded polyglutamine tract. This misfolded protein disrupts cellular function, leading to neuronal death. Normal alleles have ≤26 repeats, 27–35 are intermediate (risk of expansion), 36–39 show reduced penetrance,...
Social Anxiety Disorder01:28

Social Anxiety Disorder

Social anxiety disorder, also known as social phobia, is characterized by an intense fear of social situations where one might face humiliation, rejection, embarrassment, or negative evaluation. This disorder leads individuals to avoid activities like casual conversations, public speaking, or seemingly simple tasks such as eating, signing documents, or swimming, in public settings. Its impact extends beyond discomfort, often significantly interfering with daily functioning and quality of life.
Cystic Fibrosis: Pathogenesis01:23

Cystic Fibrosis: Pathogenesis

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Related Experiment Video

Updated: Jun 8, 2026

A Detailed Protocol for Perspiration Monitoring Using a Novel, Small, Wireless Device
05:32

A Detailed Protocol for Perspiration Monitoring Using a Novel, Small, Wireless Device

Published on: November 24, 2016

Familial primary hyperhidrosis: a disabling social disease.

I F Aini1, D M Zamrin, O S M Joanna

  • 1Division of Cardiothoracic Surgery, Heart and Lung Centre, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaakob Latif, 56000 Cheras, Kuala Lumpur, Malaysia.

La Clinica Terapeutica
|October 16, 2010
PubMed
Summary

Primary hyperhidrosis affects 2-5% of people and can be genetically linked. Video-assisted thoracoscopic sympathectomy offers a minimally invasive and effective treatment for this socially disabling condition.

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Related Experiment Videos

Last Updated: Jun 8, 2026

A Detailed Protocol for Perspiration Monitoring Using a Novel, Small, Wireless Device
05:32

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Published on: November 24, 2016

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
03:45

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model

Published on: August 8, 2022

Area of Science:

  • Medical Science
  • Surgical Innovation

Background:

  • Primary hyperhidrosis, affecting 2-5% of the population, is often hereditary and causes significant social disability.
  • Traditional treatments for hyperhidrosis have had limited success, leading to a need for more effective solutions.

Observation:

  • A familial predisposition to primary hyperhidrosis was observed in two siblings.
  • Both siblings presented with symptoms of excessive sweating impacting their daily lives.

Findings:

  • Video-assisted thoracoscopic sympathectomy (VATS) was successfully performed on both siblings.
  • The minimally invasive surgical approach resulted in minimal complications and effective treatment.

Implications:

  • VATS is a definitive and safe treatment option for primary hyperhidrosis.
  • Increased awareness of VATS for hyperhidrosis among medical practitioners is crucial for patient care.
  • Successful surgical outcomes highlight the potential for improved quality of life for hyperhidrosis patients.