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Updated: Jun 8, 2026

Implementation of a Real-Time Psychosis Risk Detection and Alerting System Based on Electronic Health Records using CogStack
07:31

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Published on: May 15, 2020

Intervention in at-risk states for developing psychosis.

Stephan Ruhrmann1, Frauke Schultze-Lutter, Andreas Bechdolf

  • 1Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Strasse 62, 50924 Cologne, Germany. stephan.ruhrmann@uk-koeln.de

European Archives of Psychiatry and Clinical Neuroscience
|October 16, 2010
PubMed
Summary

Indicated prevention strategies show promise for reducing psychosis and schizophrenia burden. Early interventions, including omega-3 fatty acids, are crucial for individuals at risk, as they require treatment, not just prevention.

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Clinical Psychology

Background:

  • Psychosis and schizophrenia pose significant individual and societal burdens.
  • Indicated prevention is an emerging strategy to combat these conditions.
  • Current research on indicated prevention is limited but shows encouraging results.

Purpose of the Study:

  • To provide an overview of current findings and ongoing research in indicated prevention for psychosis.
  • To highlight the need for interventions targeting individuals at risk for schizophrenia.
  • To explore the potential of interventions effective in both at-risk and manifest states.

Main Methods:

  • Review of pharmacological and psychotherapeutic trials in indicated prevention.
  • Analysis of studies investigating interventions for the at-risk state.
  • Examination of research on treatments applicable to both at-risk and manifest psychosis.

Main Results:

  • Pharmacological and psychotherapeutic trials have yielded encouraging results.
  • Individuals meeting at-risk criteria are considered ill and require treatment.
  • Interventions like omega-3 fatty acids show potential for treating at-risk individuals.

Conclusions:

  • Indicated prevention is a promising approach for psychosis and schizophrenia.
  • Treatment, not solely prevention, is necessary for at-risk individuals.
  • Further research into interventions for the at-risk state is warranted.