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Ocular toxoplasmosis in AIDS patients
D J Gagliuso1, S A Teich, A H Friedman
1Department of Ophthalmology, Mount Sinai School of Medicine, New York, New York.
Transactions of the American Ophthalmological Society
|January 1, 1990
Summary
Ocular toxoplasmosis, an infection by T. gondii, frequently affects AIDS patients, often presenting as retinal lesions. Effective treatment involves pyrimethamine, clindamycin, and sulfadiazine, with maintenance therapy crucial to prevent relapses.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Immunology
Background:
- Toxoplasmosis, caused by T. gondii, is a significant opportunistic infection in immunocompromised individuals, particularly those with AIDS.
- Central Nervous System (CNS) and ocular involvement are common manifestations, sometimes being the initial sign of AIDS.
- Lesions can occur in various organs, including the brain, eyes, heart, lungs, liver, spleen, and lymph nodes.