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Downgrading BIRADS 3 to BIRADS 2 category using a computer-aided microcalcification analysis and risk assessment
Georgia Giannakopoulou1, George M Spyrou, Argyro Antaraki
1Breast Unit, 1st Department of Propaedeutic Surgery, Hippokratio Hospital, School of Medicine, University of Athens, 114, Vas. Sofias Avenue, 11527 Athens, Greece. ggiannakopoulou@gmail.com
Abstract:
This paper explores the potential of a computer-aided diagnosis system to discriminate the real benign microcalcifications among a specific subset of 109 patients with BIRADS 3 mammograms who had undergone biopsy, thus making it possible to downgrade them to BIRADS 2 category. The system detected and quantified critical features of microcalcifications and classified them on a risk percentage scale for malignancy. The system successfully detected all cancers. Nevertheless, it suggested biopsy for 11/15 atypical lesions. Finally, the system characterized as definitely benign (BIRADS 2) 29/88 benign lesions, previously assigned to BIRADS 3, and thus achieved a reduction of 33% in unnecessary biopsies.
