Efficient synthesis of (6-deoxy-glycopyranosid-6-yl) sulfone derivatives and their effect on Ca2+-ATPase
Chinmoy Mukherjee1, Swatilekha Ghosh, Pinki Nandi
1Division of Molecular Medicine, Bose Institute, A.J.C. Bose Centenery Campus, P-1/12, C. I. T. Scheme VII-M, Kolkata 700054, India.
European Journal of Medicinal Chemistry
|October 19, 2010
Abstract:
Synthesis of a series of novel (6-deoxy-glycopyranosid-6-yl) sulfone derivatives has been achieved using a general synthetic strategy. Yields were excellent in every case. The synthetic compounds were evaluated for their biological potential against Ca2+-ATPase, an important enzyme involves in transporting Ca2+ across the cell membranes.


