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Published on: May 26, 2023
Anaesthesia for urgent and emergency surgery
Roland Brusseau1, Mary Ellen McCann
1Department of Anesthesiology, Perioperative and Pain Medicine, Children's Hospital Boston, Harvard Medical School, Massachusetts, USA.
Pediatric anesthesiologists must carefully assess newborns for urgent surgery, considering potential anesthetic neurotoxicity and its impact on neurocognitive development. Optimizing anesthetic management is crucial for improving surgical outcomes in neonates.
Area of Science:
- Pediatric Anesthesiology
- Neonatal Physiology
- Neuroscience
Background:
- Neonatal surgery requires specialized anesthetic care.
- Anesthetic neurotoxicity is a concern in young mammals and human infants.
- Neurocognitive delays have been linked to early-life surgery.
Purpose of the Study:
- To review anesthetic principles for urgent neonatal surgery.
- To discuss neonatal physiology and stress response suppression.
- To examine anesthetic neurotoxicity concerns and practical management strategies.
Main Methods:
- Review of general principles in pediatric anesthesiology.
- Discussion of neonatal physiology and neurodevelopment.
- Examination of anesthetic implications and specific neonatal conditions.
Main Results:
- Careful patient evaluation and prenatal history are essential.
- Understanding autonomic and nociceptive pathway development aids management.
- Anesthetic neurotoxicity and neurocognitive outcomes require consideration.
Conclusions:
- Optimizing anesthetic management improves neonatal surgical outcomes.
- Addressing anesthetic neurotoxicity concerns is vital for long-term neurodevelopment.
- Specific anesthetic strategies are necessary for complex neonatal surgical conditions.
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