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Related Concept Videos

Synthesis and Functions of Calcitonin00:51

Synthesis and Functions of Calcitonin

Calcitonin, a vital polypeptide hormone, regulates calcium levels within body fluids. It is released by the parafollicular cells, also known as C cells, situated in the follicular epithelium of the thyroid gland. Calcitonin responds to fluctuations in blood calcium levels and the influence of gastrointestinal hormones like gastrin and cholecystokinin.
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Skeleton and Calcium Homeostasis01:21

Skeleton and Calcium Homeostasis

Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations01:26

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
The Parathyroid Glands00:59

The Parathyroid Glands

The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by producing...
Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.

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Related Experiment Video

Updated: Jun 8, 2026

A Calcium Phosphate-Induced Mouse Abdominal Aortic Aneurysm Model
05:14

A Calcium Phosphate-Induced Mouse Abdominal Aortic Aneurysm Model

Published on: November 18, 2022

Tumoral calcinosis.

M V Rao1, B S Reddy, M Nadeem

  • 1Departments of Dermatology and Pathology, JIPMER, Pondicherry-605 006, India.

Indian Journal of Dermatology, Venereology and Leprology
|October 19, 2010
PubMed
Summary
This summary is machine-generated.

Tumoral calcinosis, a rare condition causing calcium deposits near joints, was studied in three middle-aged women. The report details its distinct clinical, radiological, and histopathological characteristics.

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A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro
11:30

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro

Published on: June 2, 2022

Related Experiment Videos

Last Updated: Jun 8, 2026

A Calcium Phosphate-Induced Mouse Abdominal Aortic Aneurysm Model
05:14

A Calcium Phosphate-Induced Mouse Abdominal Aortic Aneurysm Model

Published on: November 18, 2022

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro
11:30

A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro

Published on: June 2, 2022

Area of Science:

  • Nephrology
  • Rheumatology
  • Dermatopathology

Background:

  • Tumoral calcinosis is a rare disorder characterized by calcium deposition in soft tissues, often around joints.
  • The etiology of tumoral calcinosis remains incompletely understood, with various theories proposed.

Purpose of the Study:

  • To describe the clinical, radiological, and histopathological features of tumoral calcinosis.
  • To present a case series of three middle-aged female patients diagnosed with tumoral calcinosis.

Main Methods:

  • Case report analysis of three patients with tumoral calcinosis.
  • Review of clinical presentations, imaging findings (radiography), and histopathological examinations.

Main Results:

  • The patients presented with characteristic periarticular calcified masses.
  • Radiological imaging confirmed the location and extent of calcium deposits.
  • Histopathological analysis revealed specific features consistent with tumoral calcinosis.

Conclusions:

  • Tumoral calcinosis exhibits distinct clinical, radiological, and histopathological findings.
  • Early recognition of these features is crucial for accurate diagnosis and management.