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Updated: Jun 8, 2026

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
Published on: October 14, 2021
Sezary syndrome in a young woman
R T Damodaran1, S T Amladi, H R Jerajani
1Department of Dermatology & Venereology, LTM Medical College, LTMG Hospital, Sion, Mumbai - 400 022, India, .
Abstract:
A young female patient suffered for 4 months from a widespread erythrodermic rash of unknown origin, marked by a peculiar hyperaesthesia. Haematological and biopsy findings were initially non-specific. A rapid deterioration, accompanied by infiltration of the skin, lymphadenopathy and hepatosplenomegaly was suggestive of Sezary syndrome, which was confirmed by finding of 40% of the lymphocytes being atypical (Sezary cells).
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