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Generalised morphoea with lichen sclerosus et atrophicus and unusual bone changes
P V Prasad1, L Padmavathy, S Sethurajan
1Department of Dermatology, Rajah Muthiah Medical college & Hospital, Annamalainagar-608002, India, .
Indian Journal of Dermatology, Venereology and Leprology
|October 19, 2010
Summary
This case report details a rare instance of generalized morphoea co-occurring with lichen sclerosus et atrophicus (LSA) in a young male. The patient experienced severe complications, including ulcers and contractures, alongside unique bone changes.
Area of Science:
- Dermatology
- Rheumatology
- Pathology
Background:
- Morphoea is a localized form of scleroderma characterized by skin hardening.
- Lichen sclerosus et atrophicus (LSA) is a chronic inflammatory skin condition.
- The co-occurrence of morphoea and LSA is infrequently reported.
Purpose of the Study:
- To report an unusual case of generalized morphoea with LSA.
- To highlight the potential for severe complications in such cases.
- To document rare osteolytic bone changes associated with this combination.
Main Methods:
- Clinical presentation and examination of a 26-year-old male patient.
- Histopathological analysis of skin lesions.
- Radiographic assessment for bone changes.
Main Results:
- The patient presented with generalized morphoea and LSA.
- Development of significant ulcers and contractures on the left leg and hand.
- Identification of uncommon osteolytic bone abnormalities.
Conclusions:
- The simultaneous occurrence of generalized morphoea and LSA is rare.
- This combination can lead to severe cutaneous and musculoskeletal complications.
- Further investigation into the pathogenesis of associated bone changes is warranted.
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