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Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
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Published on: October 14, 2021

Mikulicz's syndrome.

K Krishna1, S Misra

  • 1Department of Skin and VD, Rural Medical College, Pravara Medical Trust, Loni BK-413 736, Maharashtra, India.

Indian Journal of Dermatology, Venereology and Leprology
|October 19, 2010
PubMed
Summary
This summary is machine-generated.

This report details a rare case of Mikulicz

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Area of Science:

  • Ophthalmology
  • Rheumatology
  • Infectious Diseases

Background:

  • Mikulicz's syndrome is a chronic, idiopathic, benign, lymphoproliferative disorder.
  • It is characterized by persistent, bilateral, non-inflammatory enlargement of the lacrimal and salivary glands.
  • Tuberculosis is a potential, though rare, underlying cause of Mikulicz's syndrome.

Purpose of the Study:

  • To report a rare case of Mikulicz's syndrome.
  • To highlight tuberculosis as an underlying etiology.
  • To discuss the clinical presentation and management of this condition.

Main Methods:

  • Case report of a 65-year-old male patient.
  • Clinical examination focusing on gland enlargement.
  • Diagnostic workup to identify underlying cause.

Main Results:

  • The patient presented with bilaterally symmetrical, asymptomatic enlargement of parotid, submandibular, and lacrimal glands.
  • Underlying tuberculosis was identified as the cause of the syndrome.
  • The condition was successfully managed.

Conclusions:

  • Mikulicz's syndrome can be associated with underlying infections like tuberculosis.
  • Thorough investigation is crucial to identify the etiology.
  • Early diagnosis and treatment are essential for favorable outcomes.