Correlation of isolates from pyoderma and carrier sites.

Area of Science:

• Dermatology
• Microbiology
• Clinical Science

Background:

• Pyoderma is a common skin infection.
• Understanding the source of pyoderma-causing bacteria is crucial for effective treatment.
• The relationship between bacteria found on pyoderma lesions and those in normal skin or nasal flora requires further investigation.

Purpose of the Study:

• To investigate the correlation between bacterial isolates from pyoderma lesions and those from normal skin and nasal flora in patients.
• To identify the predominant microorganisms responsible for pyoderma and their antibiotic susceptibility.

Main Methods:

• A study involving 100 patients diagnosed with pyoderma.
• Collection of swabs from pyoderma lesions, healthy distant skin, and anterior nares for each patient.
• Microscopic examination, bacterial culture, and antibiotic susceptibility testing were performed on collected samples.

Main Results:

• Identical bacterial isolates were found between pyoderma lesions and normal skin/nasal flora in 37% of cases.
• Staphylococcus aureus was the primary causative agent, identified in 35 out of 37 cases.
• Antibiotic susceptibility patterns were consistent in 12 of the 37 cases with identical isolates.

Conclusions:

• A significant correlation exists between bacteria found on pyoderma lesions and an individual's normal skin and nasal microbiome.
• Staphylococcus aureus is the predominant pathogen in these pyoderma cases.
• Findings suggest that the patient's own flora may play a role in the pathogenesis of pyoderma.