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Correlation of isolates from pyoderma and carrier sites
1Department of Dermatology, Government Medical College, Patiala - 147001, India.
Abstract:
100 cases of pyoderma were studied to find out whether there is any correlation between isolates from pyodermas, normal skin and nasal flora of the individual. From each patient six swabs were taken, two each from the lesion, healthy skin distant from the lesion and anterior nares. One swab from each site was used for direct microscopic examination and the other for culture and antibiotic susceptibility study. Isolates from lesion and normal skin and/or nose were identical in 37% cases of pyodermas. Isolates from lesion and normal skin were identical in 16% of cases; from lesion and nose in 14% cases, from all the three sites i.e., lesion, skin and nose in 7%. Staphylococcus aureus was the causative organism in 35 out of these 37 cases. Only in 2 cases was Staph albus isolated. In addition, antibiotic susceptibility pattern of the isolates were also the same in 12 out of these 37 cases.
Insights
A study of 100 pyoderma cases found a significant correlation between skin bacteria on lesions and normal skin or nasal flora. This suggests potential links between pyoderma and an individual's normal bacterial microbiome.
Area of Science:
- Dermatology
- Microbiology
- Clinical Science
Background:
- Pyoderma is a common skin infection.
- Understanding the source of pyoderma-causing bacteria is crucial for effective treatment.
- The relationship between bacteria found on pyoderma lesions and those in normal skin or nasal flora requires further investigation.
Purpose of the Study:
- To investigate the correlation between bacterial isolates from pyoderma lesions and those from normal skin and nasal flora in patients.
- To identify the predominant microorganisms responsible for pyoderma and their antibiotic susceptibility.
Main Methods:
- A study involving 100 patients diagnosed with pyoderma.
- Collection of swabs from pyoderma lesions, healthy distant skin, and anterior nares for each patient.
- Microscopic examination, bacterial culture, and antibiotic susceptibility testing were performed on collected samples.
Main Results:
- Identical bacterial isolates were found between pyoderma lesions and normal skin/nasal flora in 37% of cases.
- Staphylococcus aureus was the primary causative agent, identified in 35 out of 37 cases.
- Antibiotic susceptibility patterns were consistent in 12 of the 37 cases with identical isolates.
Conclusions:
- A significant correlation exists between bacteria found on pyoderma lesions and an individual's normal skin and nasal microbiome.
- Staphylococcus aureus is the predominant pathogen in these pyoderma cases.
- Findings suggest that the patient's own flora may play a role in the pathogenesis of pyoderma.
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