Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Centrifugation01:05

Centrifugation

Centrifugation is a separation technique based on differences in density or size. It is commonly used to separate solids from aqueous interferents. During centrifugation, the sample is placed in centrifugation tubes and spun at high angular velocity, which allows centrifugal force to act differentially on the different densities or masses of the components. After spinning, the supernatant liquid is decanted. Depending on the specific application, either the pellet or the supernatant is retained...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Mechanism of Filopodia Formation01:39

Mechanism of Filopodia Formation

Filopodia are thin, actin-rich cellular protrusions that play an important role in many fundamental cellular functions. They vary in their occurrence, length, and positioning in different cell types, suggesting their diverse roles.
Their main function is to guide migrating cells during normal tissue morphogenesis or cancer metastasis by recognizing and making initial contacts with the extracellular matrix. However, they can also act as stationary cell anchors or help to establish communication...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Multipotency and Niche of Bulge Stem Cell01:06

Multipotency and Niche of Bulge Stem Cell

A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thalamocortical Projections Are Significantly Impaired in the R6/2 Mouse Model of Huntington's Disease.

eNeuro·2022
Same author

Formation of nanostructures on magnesium alloy by anodization for potential biomedical applications.

Materials today. Communications·2021
Same author

Electrochemical fabrication of TiO<sub>2</sub> micro-flowers for an efficient intracellular delivery using nanosecond light pulse.

Materials chemistry and physics·2021
Same author

Fabrication of TiO<sub>2</sub> microspikes for highly efficient intracellular delivery by pulse laser-assisted photoporation.

RSC advances·2021
Same author

Cost and cost-effectiveness of health behavior change interventions implemented with self-help groups in Bihar, India.

PloS one·2019
Same author

Drug release characteristics of quercetin-loaded TiO<sub>2</sub> nanotubes coated with chitosan.

International journal of biological macromolecules·2016
Same journal

Severe combined immunodeficiency (SCID) with pigmentary mosaicism: A coincidental occurrence in a child.

Indian journal of dermatology, venereology and leprology·2026
Same journal

Agminated multifocal eruptive lobular capillary haemangiomas - An uncommon presentation.

Indian journal of dermatology, venereology and leprology·2026
Same journal

Patch testing in India: Are we missing clinically relevant allergens?

Indian journal of dermatology, venereology and leprology·2026
Same journal

Double-loading technique for improved suspension retention on the recipient site in non-cultured epidermal cell suspension (NCES).

Indian journal of dermatology, venereology and leprology·2026
Same journal

Late-onset metastatic melanoma arising from a medium-sized congenital melanocytic naevus.

Indian journal of dermatology, venereology and leprology·2026
Same journal

Custom-compounded glycine-proline jelly for ulcers in prolidase deficiency.

Indian journal of dermatology, venereology and leprology·2026
See all related articles

Related Experiment Video

Updated: Jun 8, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Keratoacanthoma centrifugum marginatum.

S Rastogi1, P Kumar, K Swarup

  • 1Department of Department of Dermatology, BRD Medical College, Gorakhpur-273013, India, .

Indian Journal of Dermatology, Venereology and Leprology
|October 19, 2010
PubMed
Summary
This summary is machine-generated.

This report details a rare case of multiple keratoacanthoma centrifugum marginatum in a 38-year-old male. Diagnosis was confirmed via histopathological examination of skin nodules.

More Related Videos

Sample Preparation Method of Scanning and Transmission Electron Microscope for the Appendages of Woodboring Beetle
10:09

Sample Preparation Method of Scanning and Transmission Electron Microscope for the Appendages of Woodboring Beetle

Published on: February 3, 2020

Related Experiment Videos

Last Updated: Jun 8, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
06:15

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Sample Preparation Method of Scanning and Transmission Electron Microscope for the Appendages of Woodboring Beetle
10:09

Sample Preparation Method of Scanning and Transmission Electron Microscope for the Appendages of Woodboring Beetle

Published on: February 3, 2020

Area of Science:

  • Dermatology
  • Oncology
  • Pathology

Background:

  • Keratoacanthoma centrifugum marginatum (KCM) is a rare, rapidly growing skin tumor.
  • KCM typically presents as multiple, firm, non-tender nodules.
  • Understanding KCM variants is crucial for accurate diagnosis and management.

Purpose of the Study:

  • To report a rare case of KCM.
  • To describe the clinical and histopathological features of KCM.
  • To highlight the importance of recognizing rare KCM variants.

Main Methods:

  • Case presentation of a 38-year-old male patient.
  • Clinical examination of skin lesions.
  • Histopathological examination for diagnosis confirmation.

Main Results:

  • The patient presented with multiple, firm, non-tender, skin-colored nodules of varying sizes.
  • Histopathological examination confirmed the diagnosis of keratoacanthoma centrifugum marginatum.
  • The findings represent a rare variant of keratoacanthoma.

Conclusions:

  • This case highlights a rare presentation of keratoacanthoma centrifugum marginatum.
  • Accurate histopathological diagnosis is essential for identifying rare KCM variants.
  • Further research into KCM pathogenesis and treatment is warranted.