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Related Experiment Video

Updated: Jun 8, 2026

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

Lichen simplex chronicus - A Psychocutaneous disorder?

V D Sanjana¹, R J Fernandez

¹Department of Dermatology and Venereology, KEM Hospital, Parel, Mumbai-400012, India.

Indian Journal of Dermatology, Venereology and Leprology

|October 19, 2010

Summary

This summary is machine-generated.

This study investigated lichen simplex chronicus, a skin condition linked to emotional factors. Researchers found that while both anxiety and depression were present, depression showed a stronger correlation with the severity of itching in patients.

Related Experiment Videos

Last Updated: Jun 8, 2026

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

Area of Science:

Psychodermatology
Psychiatry
Dermatology

Background:

Lichen simplex chronicus is a psychocutaneous disorder influenced by emotional factors.
Understanding the psyche's role is crucial for managing this condition.

Purpose of the Study:

To determine the involvement of psychological factors in lichen simplex chronicus.
To explore the relationship between mental state and pruritus severity.

Main Methods:

Forty-six patients with lichen simplex chronicus were assessed.
Pruritus severity was rated on a 10-point scale.
Psychiatric interviews utilized the Hamilton anxiety-depression scale.

Main Results:

Anxiety and depression scores did not exceed 50% of the scale.
A correlation between depression and pruritus was observed.
Depression appeared more related to pruritus than anxiety.

Conclusions:

The exteriorization of inner turmoil through itching may explain lower anxiety scores.
Depression may play a more significant role in the pruritus of lichen simplex chronicus than anxiety.