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Related Concept Videos

Assessment of the Mouth01:26

Assessment of the Mouth

A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Oral Cavity01:11

Oral Cavity

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The Oral Microbiota01:27

The Oral Microbiota

The oral microbiome includes a complex ecosystem comprising over 700 microbial species, identified through genomic sequencing and culture-based analyses to date. This community includes a core microbiome, found universally among individuals, and a variable component influenced by environmental factors such as diet, lifestyle, and host genetics. Site-specific conditions, including oxygen gradients, pH levels, and nutrient availability, determine the spatial distribution of these microorganisms...
Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Herpes01:28

Herpes

Herpes simplex type 1 (HSV‑1) is a widespread pathogen responsible for orolabial lesions. It is an enveloped, double-stranded DNA (dsDNA) virus belonging to the family Herpesviridae. Once the virus infects a host cell, its double‑stranded DNA genome is delivered into the nucleus, where a coordinated cascade of immediate‑early, early, and late gene expression directs viral DNA replication, structural protein synthesis, and virion assembly. After primary infection of epithelial cells, HSV-1...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Related Experiment Video

Updated: Jun 8, 2026

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients
05:26

Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients

Published on: March 1, 2024

Oral leucoplakia.

R K Jain1, M Kumar, O Nath

  • 1Departments of Otolaryngology, Institute of Medical Sciences, Baranas Hindu University, Varanasi, India.

Indian Journal of Dermatology, Venereology and Leprology
|October 19, 2010
PubMed
Summary
This summary is machine-generated.

Oral leucoplakia, often linked to tobacco use, primarily affects the elderly. Early detection and treatment, such as cryosurgery or vitamin A, are crucial for managing this oral potentially malignant disorder.

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Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection
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Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection

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Examination of Oral Candida Infection in Primary Sjögren's Syndrome Patients
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Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection
05:42

Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection

Published on: August 11, 2023

Area of Science:

  • Oral Medicine
  • Oncology
  • Dermatology

Background:

  • Oral leucoplakia is a potentially malignant oral disorder.
  • Tobacco addiction is a significant risk factor.
  • Understanding its clinical and histological features is vital for management.

Purpose of the Study:

  • To investigate the clinical and histological characteristics of oral leucoplakia.
  • To assess the prevalence of associated conditions like oral submucous fibrosis.
  • To evaluate treatment outcomes for oral leucoplakia.

Main Methods:

  • Retrospective analysis of oral leucoplakia patient data.
  • Clinical examination for site and type of lesion.
  • Histopathological examination for dysplasia and other changes.
  • Assessment of treatment efficacy.

Main Results:

  • Oral leucoplakia predominantly affects the elderly, with 80.8% linked to tobacco use.
  • Buccal mucosa is the most common site (67.33%); homogenous type is most frequent (57.35%).
  • Oral submucous fibrosis was present in 26-48% of cases; dysplasia in 17.65%; malignant transformation in 2.94%.

Conclusions:

  • Cryosurgery shows excellent therapeutic results for oral leucoplakia.
  • High-dose vitamin A is effective for resistant cases.
  • Regular monitoring and prompt treatment are essential for managing oral leucoplakia and preventing malignant transformation.