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Increased Body Temperature

Increased Body Temperature

A body temperature above 38°C (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in response to an infection or illness.

Types of Fever

Types of Fever

Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:

Methods of reducing fever

Methods of reducing fever

The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:

Patterns of Fever

Patterns of Fever

Before understanding the types and patterns of fever, it is essential to know its phases.

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...

Rheumatic Heart Disease I: Introduction

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...

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Related Experiment Video

Updated: Jun 8, 2026

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

Published on: May 16, 2025

Fevers and the rheumatologist.

Prudence Joan Manners¹, Robin Guttinger

¹School of Paediatrics and Child Health, University of Western Australia, c/- Princess Margaret Hospital for Children, Perth, Australia. pmanners@meddent.uwa.edu.au

Indian Journal of Pediatrics

|October 19, 2010

Summary

This summary is machine-generated.

Pediatric rheumatologists manage fevers caused by inflammatory conditions. This review details seven hereditary recurrent fever syndromes, their diagnosis, and treatments.

Related Experiment Videos

Last Updated: Jun 8, 2026

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

Published on: May 16, 2025

Area of Science:

Pediatric Rheumatology
Genetics
Immunology

Background:

Fevers in children often stem from infections, malignancies, or inflammatory conditions.
Rheumatologists play a key role in managing inflammatory conditions associated with fevers.
Seven distinct hereditary recurrent fever syndromes have been identified, each linked to a specific gene mutation.

Purpose of the Study:

To provide a comprehensive overview of hereditary recurrent fever syndromes within the context of pediatric rheumatological conditions.
To elucidate diagnostic approaches for these rare genetic inflammatory disorders.
To outline current treatment strategies for each identified syndrome.

Main Methods:

Literature review and synthesis of existing data on hereditary recurrent fever syndromes.
Detailed discussion of diagnostic criteria and genetic underpinnings.
Analysis of current therapeutic recommendations and management guidelines.

Main Results:

Seven hereditary recurrent fever syndromes are detailed: CINCA, FACS, FMF, HIDS, MWS, PAPA, and TRAPS.
Each syndrome presents with recurring fevers and is associated with a defined single-gene mutation.
Diagnostic pathways and treatment options for each condition are reviewed.

Conclusions:

Hereditary recurrent fever syndromes represent a significant group of pediatric inflammatory conditions.
Accurate diagnosis relies on recognizing characteristic clinical features and genetic testing.
Tailored treatment strategies are crucial for managing these autoinflammatory disorders effectively.