Irvine Page lecture. Legacies of Irvine H. Page

Irvine Page has played a singularly important part in the field of hypertension for almost 60 years. His first contributions were published in the early 1930s and his most recent, Hypertension Mechanisms, in 1987. The present review outlines some of his accomplishments. It focuses on five areas where his pre-eminence is a matter of record, the renin-angiotensin system, serotonin, the mosaic theory, treatment of hypertension and public and professional advocacy of the recognition of this condition and its effects in daily life.