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Updated: Jun 8, 2026

Defining Gene Functions in Tumorigenesis by Ex vivo Ablation of Floxed Alleles in Malignant Peripheral Nerve Sheath Tumor Cells
Published on: August 25, 2021
[Molecular target therapy in cancer]
1Medical Oncology Division, Kinki University School of Medicine.
Abstract:
Many molecular target drugs have been developed based on the progress in the study of molecular biology. Majority of treatment for common malignancy include molecular target drugs. Patients selection has become possible by pharmacogenomical tests in some molecular target therapy. Development of active molecular target therapy will enable the increment of curative populations even in advanced malignancies. Intensive proof of principle study will open doors for the identification of new molecular targets.
Insights
Molecular target drugs, developed from molecular biology advancements, are key in treating common cancers. Pharmacogenomic tests enable patient selection for targeted therapies, expanding curative potential even in advanced disease.
Area of Science:
- Molecular biology
- Pharmacogenomics
- Oncology
Context:
- Molecular target drugs are increasingly central to cancer treatment.
- Advancements in molecular biology underpin drug development.
- Pharmacogenomic testing facilitates personalized medicine approaches.
Purpose:
- To highlight the role of molecular target drugs in oncology.
- To emphasize the importance of pharmacogenomics in patient selection.
- To discuss the potential for new molecular targets in advanced malignancies.
Summary:
- Molecular target drugs, a product of molecular biology research, form the basis of many common malignancy treatments.
- Patient selection for molecular target therapy is increasingly guided by pharmacogenomic tests.
- Further research into molecular targets promises to improve cure rates, even for advanced cancers.
Impact:
- Enables precision medicine in oncology.
- Expands treatment options for advanced malignancies.
- Drives discovery of novel therapeutic targets.
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