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Published on: January 7, 2019
A carbapenem-resistant Klebsiella pneumoniae isolate harboring KPC-1 from Italy
Abstract:
Carbapenem-resistant gram-negative pathogens represent an emerging threat to the management of hospital-acquired infections. Although the isolation of carbapenem-resistant enterobacteriaceae remains unusual, the frequency of carbapenemases producing Klebsiella pneumoniae is increasing in different geographic regions: the majority of isolates has been collected in the USA, but recently KPC-producing K. pneumoniae were reported from China, Israel, Greece, France, Norway and Sweden. We report a KPC 1-producing K. pneumoniae isolate from Italy. This datum enlarges the geographical area where the KPC-producing K. pneumoniae strains are diffuse.
Insights
Carbapenem-resistant gram-negative infections are a growing concern. A KPC-1 producing Klebsiella pneumoniae strain was identified in Italy, expanding the known geographical spread of this resistant pathogen.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Antimicrobial Resistance
Background:
- Carbapenem-resistant gram-negative pathogens pose a significant threat to hospital-acquired infections.
- Carbapenemase-producing Klebsiella pneumoniae (KPC) is an increasing concern globally.
Observation:
- KPC-producing K. pneumoniae isolates have been reported in various countries including the USA, China, Israel, Greece, France, Norway, and Sweden.
- The isolation of carbapenem-resistant Enterobacteriaceae remains uncommon.
Findings:
- A KPC-1 producing Klebsiella pneumoniae isolate was identified in Italy.
- This finding represents the first report of KPC-producing K. pneumoniae in Italy.
Implications:
- This discovery expands the known geographical distribution of KPC-producing K. pneumoniae.
- Surveillance and infection control measures are crucial to manage the spread of carbapenem-resistant pathogens.
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