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Updated: Jun 8, 2026

Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
Prevalence, pattern and risk factors for undernutrition in early infancy using the WHO Multicentre Growth Reference:
Bolajoko O Olusanya1, Sheila L Wirz, James K Renner
1Department of Community Health and Primary Care, College of Medicine, University of Lagos, Nigeria. boolusanya@aol.com
Insights
Undernutrition is common in Nigerian infants during the first three months. Early detection is possible at routine immunisation clinics, with maternal and perinatal factors serving as key predictors.
Area of Science:
- Public Health
- Pediatrics
- Nutritional Epidemiology
Background:
- Limited data exists on infant nutritional status in the first three months, especially in populations with high rates of non-hospital births.
- Early infancy is a critical period for growth and development, making nutritional status assessment crucial.
Purpose of the Study:
- To determine the prevalence, pattern, and risk factors of undernutrition in infants aged 0-3 months.
- To identify maternal and infant factors associated with undernutrition in a Nigerian setting.
Main Methods:
- Cross-sectional study involving 5888 infants attending routine immunisation clinics in Lagos, Nigeria.
- Utilized World Health Organisation's Multicentre Growth Reference (WHO-MGR) for nutritional assessment (weight-for-age, height/length-for-age, BMI-for-age).
- Multivariable logistic regression analyses were employed to explore associated maternal and infant factors.
Main Results:
- High prevalence of undernutrition: 13.8% underweight, 30.8% stunted, 10.0% wasted.
- 61.6% of infants were adequately nourished, while 3.3% were undernourished across all three measures.
- Intrauterine growth restriction, maternal age, multiple pregnancies, gender, maternal education, residence, parity, antenatal care, place of delivery, and hyperbilirubinaemia were significant predictors.
Conclusions:
- Undernutrition is prevalent in early infancy in this population and can be identified during routine immunisation visits.
- Maternal and perinatal history provides valuable predictive information for undernutrition, particularly in resource-poor settings with many non-hospital births.
Abstract:
This cross-sectional study set out to determine the prevalence, pattern and risk factors for undernutrition during early infancy in a setting with substantial non-hospital births against the backdrop of limited evidence on nutritional status in the first three months of life based on an exclusively breast-fed reference population. Undernutrition based on z-scores below -2 for weight-for-age, height/length-for-age and body-mass-index-for-age among infants (0-3 months) attending clinics for routine Bacille de Calmette-Guérin (BCG) immunisation in Lagos, Nigeria from July 2005 to March 2008 was determined using current World Health Organisation's Multicentre Growth Reference (WHO-MGR). Maternal and infant factors associated with undernutrition were explored with multivariable logistic regression analyses. Of the 5888 full-term infants enrolled 51% were born outside hospital and 99.4% were exclusively breast-fed. 811 (13.8%) were underweight (weight-for-age), 1802 (30.8%) were stunted (height/length-for-age) and 579 (10.0%) were wasted (body-mass-index-for-age). Altogether, 3635 (61.6%) infants were not undernourished while 192 (3.3%) were undernourished by all three nutritional measures. Intrauterine growth restriction was a significant contributor to undernutrition. Maternal age, multiple pregnancies and gender were associated with all nutritional indices. Additionally, maternal education, ownership/type of residence, parity, antenatal care, place of delivery and hyperbilirubinaemia were predictive of underweight, stunting and wasting. We conclude that undernutrition is prevalent in the first three months of life in this population and can be detected early at routine immunisation clinics shortly after birth. Maternal/perinatal history offers valuable predictors in resource-poor communities where the majority of births occur outside hospital.
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