Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Urinary Bladder

Urinary Bladder

The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Prophylactic antibiotic in pubertal testicular torsion: Is it Justified?

Journal of pediatric urology·2026

Same author

Pre-pubertal testicular torsion: A critical analysis of outcomes from a tertiary care center.

Journal of pediatric urology·2026

Same author

Corrigendum to: Phentolamine rescue for glanular ischemia in the setting of inadvertent administration of high-dose 1:1,000 epinephrine to glans in distal hypospadias surgery [Urol Case Rep, (59), March 2025, 102941. PMID: 39925745].

Urology case reports·2026

Same author

Autologous muscle precursor cell injection into the bladder neck improves the symptoms of stress urinary incontinence in adult females.

Stem cells translational medicine·2025

Same author

Pelvic Mass in a Pediatric Patient: A Rare Case of Extraosseous Ewing Sarcoma.

Urology·2025

Same author

Phentolamine rescue for glanular ischemia in the setting of inadvertent administration of high-dose 1:1,000 epinephrine to glans in distal hypospadias surgery.

Urology case reports·2025

Search research articles

Related Experiment Video

Updated: Jun 7, 2026

Tissue Engineering of a Human 3D in vitro Tumor Test System

Tissue Engineering of a Human 3D in vitro Tumor Test System

Published on: August 6, 2013

Bladder tissue engineering.

Irina Stanasel¹, Majid Mirzazadeh, John J Smith

¹Department of Urology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157, USA.

The Urologic Clinics of North America

|October 20, 2010

Summary

This summary is machine-generated.

Surgical bladder reconstruction, like augmentation cystoplasty, is an option when conservative treatments fail. Tissue engineering offers a regenerative approach using the body's own cells and materials to restore bladder function.

More Related Videos

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Published on: August 9, 2012

Surgical Model for Single-Staged Tissue-Engineered Urothelial Tubes in Minipigs

Surgical Model for Single-Staged Tissue-Engineered Urothelial Tubes in Minipigs

Published on: July 5, 2024

Related Experiment Videos

Last Updated: Jun 7, 2026

Tissue Engineering of a Human 3D in vitro Tumor Test System

Tissue Engineering of a Human 3D in vitro Tumor Test System

Published on: August 6, 2013

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Evaluation of Biomaterials for Bladder Augmentation using Cystometric Analyses in Various Rodent Models

Published on: August 9, 2012

Surgical Model for Single-Staged Tissue-Engineered Urothelial Tubes in Minipigs

Surgical Model for Single-Staged Tissue-Engineered Urothelial Tubes in Minipigs

Published on: July 5, 2024

Area of Science:

Regenerative Medicine
Urology
Biomaterials Science

Background:

Bladder dysfunction impacts storage and emptying, necessitating treatment.
Conservative methods may fail, leading to surgical intervention.
Augmentation cystoplasty uses intestinal segments for bladder reconstruction.

Purpose of the Study:

To explore tissue engineering as an alternative to traditional bladder reconstruction.
To highlight the potential of regenerative medicine in restoring bladder function.
To review current cell sources for tissue-engineered bladders.

Main Methods:

Investigating tissue engineering strategies for bladder repair.
Utilizing scaffolds or cell-seeded matrices for regeneration.
Exploring various cell sources, including stem cells and autologous bladder cells.

Main Results:

Tissue engineering aims to restore original bladder structure and function.
Cellular components and biomaterials are key to regenerative approaches.
Autologous bladder cells are currently the preferred source for cell seeding.

Conclusions:

Tissue engineering presents a promising alternative for bladder reconstruction.
Regenerative strategies leverage the body's innate healing capabilities.
Further research into optimal cell sources and scaffold materials is ongoing.