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Related Concept Videos

Intrauterine Drug Delivery Systems01:21

Intrauterine Drug Delivery Systems

Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...
Birth Control Methods01:22

Birth Control Methods

Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although vasectomy...
In Vitro Fertilization01:24

In Vitro Fertilization

In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
Dosage Interval and Administration Route: Determination Methods01:19

Dosage Interval and Administration Route: Determination Methods

A medication’s effectiveness largely depends on its appropriate dosage and the route of administration. Dosage ensures that a sufficient drug concentration is maintained in the bloodstream to elicit the desired therapeutic effect without causing toxicity. The route of administration affects the drug's bioavailability, rate of absorption, and onset of action, which are crucial for achieving optimal therapeutic outcomes. Drug dosage calculations are critical to tailoring therapy to individual...
Modified-Release Drug Delivery Systems: Rate-Programmed I01:22

Modified-Release Drug Delivery Systems: Rate-Programmed I

Rate-programmed drug delivery systems (DDS) are designed to release drugs at specific, controlled rates to maintain consistent therapeutic levels. These systems are categorized based on their release mechanisms, including dissolution-controlled DDS, diffusion-controlled DDS, and combined dissolution-diffusion-controlled DDS.In dissolution-controlled DDS, the release rate depends on the slow dissolution of the drug itself or the surrounding matrix. Drugs with inherently slow dissolution rates,...
Uterine Tubes01:16

Uterine Tubes

The uterine or fallopian tubes function as the conduit through which oocytes travel from the ovaries to the uterus. Each fallopian tube measures approximately 10 to 13 cm long and is anatomically divided into the infundibulum, ampulla, isthmus, and interstitial part (or intramural segment). The infundibulum is characterized by its funnel shape and features extensions called fimbriae which reach towards the peritoneal cavity. These fimbriae play a critical role during ovulation as they extend...

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Related Experiment Video

Updated: Jun 7, 2026

Laparoscopic Extracorporeal Knot-Tying for Uterine Vessel Occlusion during Hysterectomy with Cervical Cerclage in Large Uteri
05:21

Laparoscopic Extracorporeal Knot-Tying for Uterine Vessel Occlusion during Hysterectomy with Cervical Cerclage in Large Uteri

Published on: September 12, 2025

Algorithm for nonvisible strings of levonorgestrel intrauterine system.

George A Vilos1, Robert Di Cecco, Jennifer Marks

  • 1St. Joseph's Health Care, Department of Obstetrics and Gynecology, The University of Western Ontario, London, Ontario, Canada. george.vilos@sjhc.london.on.ca

Journal of Minimally Invasive Gynecology
|October 20, 2010
PubMed
Summary

Strings from a levonorgestrel intrauterine system (LNG-IUS) were not visible in the cervix. The device was found in the omentum and removed surgically, leading to a proposed algorithm for missing IUS strings.

Related Experiment Videos

Last Updated: Jun 7, 2026

Laparoscopic Extracorporeal Knot-Tying for Uterine Vessel Occlusion during Hysterectomy with Cervical Cerclage in Large Uteri
05:21

Laparoscopic Extracorporeal Knot-Tying for Uterine Vessel Occlusion during Hysterectomy with Cervical Cerclage in Large Uteri

Published on: September 12, 2025

Area of Science:

  • Reproductive Medicine
  • Minimally Invasive Surgery
  • Medical Device Complications

Background:

  • Intrauterine devices (IUDs) are common contraceptives.
  • Complications such as missing strings can occur.
  • Rarely, IUDs can migrate to extrauterine locations.

Purpose of the Study:

  • To report a rare case of levonorgestrel intrauterine system (LNG-IUS) migration.
  • To describe the laparoscopic retrieval of an omental LNG-IUS.
  • To propose an algorithm for managing missing IUD strings.

Main Methods:

  • Case report of a patient with nonvisible LNG-IUS strings.
  • Diagnostic imaging to locate the misplaced device.
  • Laparoscopic surgery for device retrieval.
  • Development of a management algorithm.

Main Results:

  • The levonorgestrel intrauterine system (LNG-IUS) was not visible in the cervical canal.
  • The LNG-IUS was located within the omentum.
  • Successful laparoscopic retrieval of the omental LNG-IUS was achieved.
  • A novel algorithm for managing missing IUD strings was devised.

Conclusions:

  • Omental migration of an LNG-IUS is a rare but possible complication.
  • Laparoscopic surgery is an effective method for retrieving migrated IUDs.
  • A structured approach is beneficial for diagnosing and managing missing IUD strings.