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[Histoplasmin and paracoccidioidin reactions in Serra de Pereiro. (Ceara State--Brazil)]
M J Diógenes1, H M Gonçalves, A C Mapurunga
1Departamento de Medicina Clínica, Centro de Ciências da Saúde CCST, Universidade Federal do Ceará UFC, Ceará, Brasil.
Abstract:
Intradermal tests using histoplasmin and paracoccidioidin antigens were performed in 138 persons from Pereiro, Ceará, Brazil. The results were positive in 61.5% and 32.5% with histoplasmin and paracoccidioidin antigens respectively. These results suggest infection by H. capsulatum and P. brasiliensis in the people living in the studied area. New studies are necessary to detect histoplasmosis and paracoccidioidomycosis as clinical diseases in that region.
Insights
High rates of fungal infections were found in Brazil. Intradermal tests showed significant exposure to Histoplasma capsulatum and Paracoccidioides brasiliensis, indicating a need for further clinical disease detection.
Area of Science:
- Mycology
- Infectious Diseases
- Epidemiology
Context:
- High prevalence of fungal infections in endemic areas.
- Limited data on clinical manifestations of histoplasmosis and paracoccidioidomycosis in Pereiro, Ceará, Brazil.
Purpose:
- To assess the seroprevalence of Histoplasma capsulatum and Paracoccidioides brasiliensis infections in Pereiro, Ceará, Brazil.
- To determine the positivity rates of intradermal tests using specific fungal antigens.
Summary:
- Intradermal testing with histoplasmin and paracoccidioidin antigens was conducted on 138 individuals in Pereiro, Ceará.
- Positive reactions were observed in 61.5% for histoplasmin and 32.5% for paracoccidioidin.
- Results indicate widespread exposure to H. capsulatum and P. brasiliensis in the population.
Impact:
- Suggests a significant burden of exposure to endemic dimorphic fungi.
- Highlights the necessity for further research into clinical disease detection and management.
- Provides baseline epidemiological data for public health interventions in the region.