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Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight, compared...
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...
Current Trends in Nursing II01:30

Current Trends in Nursing II

Trends in nursing are multifactorial and associated with changes in society, within the nursing profession, and in other professions. Notably, telehealth and remote nursing contribute to successful healthcare delivery for numerous patients and help reduce stress for nurses due to nursing shortages. Nurses can reach patients, monitor their conditions, and interact with them using computers, audio, visual accessories, and telephones—for example, remote patient monitoring systems. Likewise,...
Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...

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Adult and Pediatric Porcine Model of Acute Volume Overload
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Peering into the future: pediatrics in a changing world.

Laurel K Leslie1, Kenneth M Slaw, Anne Edwards

  • 1Pediatrics and Medicine, Tufts Medical Center/Floating Hospital for Children, 800 Washington St, No. 345, Boston, MA 02111, USA. lleslie@tuftsmedicalcenter.org

Pediatrics
|October 20, 2010
PubMed
Summary

The American Academy of Pediatrics developed the PEER cycle to help pediatric health professionals navigate rapid changes. This Prepare, Envision, Engage, Reshape model fosters proactive adaptation in child healthcare.

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Area of Science:

  • Pediatric healthcare transformation
  • Child and adolescent health trends
  • Healthcare delivery innovation

Background:

  • Healthcare is undergoing rapid, unpredictable change.
  • The American Academy of Pediatrics formed the Vision of Pediatrics (VOP) 2020 Task Force in 2008 to address these shifts.
  • Demographic, socioeconomic, health status, delivery, and scientific advances impact child health.

Purpose of the Study:

  • To identify forces affecting child and adolescent health.
  • To determine implications for the field of pediatrics.
  • To propose a framework for managing continuous change in pediatrics.

Main Methods:

  • Convened the Vision of Pediatrics (VOP) 2020 Task Force.
  • Identified eight key megatrends influencing pediatrics.
  • Proposed the Prepare, Envision, Engage, and Reshape (PEER) change model.

Main Results:

  • Identified significant megatrends impacting child and adolescent health.
  • Concluded that a continuous process is needed to prepare for and lead change.
  • Developed the PEER cycle as a framework for ongoing adaptation and strategic change.

Conclusions:

  • The pediatric profession must adopt a continuous process to anticipate and lead change.
  • The PEER cycle (Prepare, Envision, Engage, Reshape) provides a structured approach for managing change.
  • This cyclical model supports proactive adaptation to evolving trends in child health and healthcare delivery.