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Updated: Jun 7, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[Clinical study on modified maxillomandibular advancement for the treatment of obstructive sleep apnea syndrome]
1Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, China.
Objective:
To evaluate the modified maxillomandibular advancement (MMMA) technique for the treatment of obstructive sleep apnea syndrome (OSAS) in yellow race of convex profile.
Methods:
Eight patients underwent MMMA for the treatment of OSAHS. All the patients underwent pre-surgical and postsurgical polysomnography, cephalometric analysis and objective results assessment.
Results:
The preoperative polysomnography results of the patients were as follows: apnea-hypopnea index, (40.1±16.1) per hour; lowest oxygen saturation, (72.4±7.2)%. The postoperative polysomnography results were as follows: apnea-hypopnea index, (5.4±3.8) per hour; lowest oxygen saturation, (90.6±2.1)%. The mean preoperative SNA was (80.9± 1.7)°, and the mean postoperative SNA was (82.9±1.5)°. The mean preoperative SNB was (72.5±2.6)°, and the mean postoperative SNB was (81.5±1.7)°. The mean preoperative PAS was (5.3 ±1.6) mm, and the mean postoperative PAS was (10.8 ±1.8) mm.
Conclusion:
The preliminary review has demonstrated that the modified MMA technique for the treatment of OSAS is highly effective in the treatment of severe OSAS without the significant facial profile change commonly associated with the traditional MMA technique. With the introduction of this modified MMA technique for the treatment of OSAS, skeletal surgery may be less perceived as an unattractive treatment modality due to the markedly reduced anticipated facial changes after surgery.
